Age and Gender Distribution

Oct 13, 2025 by talynt.org 97 views

Overview of Characteristics of Post-Streptococcal Acute Glomerulonephritis in Children in Children's Nephrology Division Hospital H. Adam Malik Medan Period 2017 - 2019

Introduction

Glomerulonephritis is a common kidney disease that affects children worldwide. It is characterized by inflammation of the glomerulus, a vital part of the kidney responsible for filtering waste from the blood. One form of glomerulonephritis that is often found in children is acute glomerulonephritis after streptococcus (GNAPS). This study aims to describe the characteristics of post-streptococcal acute glomerulonephritis in children treated at H. Adam Malik Hospital Medan during the period 2017 to 2019.

Background

Glomerulonephritis is a general term that refers to inflammation of the glomerulus, a part of the kidney that functions to filter waste from the blood. This disease can be caused by an immunological process that leads to the proliferation of cells in the glomerular. One form of glomerulonephritis that is often found in children is acute glomerulonephritis after streptococcus (GNAPS). GNAPS is the most common form of glomerulonephritis in the world, with more than 450,000 cases that are expected to occur every year, and most of the sufferers are children.

Methodology

The research design used in this study is descriptive with a cross-sectional design, relying on retrospective data taken from medical records. The observed data included information during the study period, from 2017 to 2019. The study aimed to describe the characteristics of post-streptococcal acute glomerulonephritis in children treated at H. Adam Malik Hospital Medan during the period 2017 to 2019.

Results

From the research conducted, there were 21 children with acute acute glomerulonephritis after streptococcus. The following is a more detailed picture of the characteristics of these children:

Age and Gender Distribution

The most common age range is 2-10 years, with a total of 14 children. The sex of the child most often affected is male, with a total of 11 people. This suggests that post-streptococcal acute glomerulonephritis is more common in young children, particularly males.

History of Infection

Five children have a history of acute respiratory infections that may contribute to the appearance of GNAPS. This suggests that respiratory tract infections may play a role in the development of post-streptococcal acute glomerulonephritis.

Nutritional Status and Parental Employment

Most children are in the normal category, with a total of 16 children. Parents' work shows that 8 fathers work as entrepreneurs, and 13 mothers act as housewives. This suggests that the nutritional status of children with post-streptococcal acute glomerulonephritis is generally normal, and that parental employment may not have a significant impact on the development of the disease.

Parental Education

Most parents have the last education at high school level, with 18 fathers and 14 mothers who graduated from high school. This suggests that parental education may not have a significant impact on the development of post-streptococcal acute glomerulonephritis.

Clinical Manifestations

The most commonly found in children with GNAPS is hypertension, occurs in 14 children. Other symptoms include macroscopic hematuria (5 children), edema (9 children), and oliguria (12 children). This suggests that hypertension is a common clinical manifestation of post-streptococcal acute glomerulonephritis.

Laboratory Results

Laboratory tests show proteinuria in 15 children, microscopic hematuria in 19 children, as well as a significant decrease in C3 complement levels in 18 children. Increased ASO titers are detected in 9 children, and there are cases of leukocyturia (12 children) and anemia (8 children). Decreased glomerular filtration rate (LFG) occurs in 10 children, accompanied by leukocytosis (9 children) and hypoalbuminemia (17 children). This suggests that laboratory tests can help diagnose post-streptococcal acute glomerulonephritis and monitor its progression.

Conclusion

From the analysis conducted, it can be concluded that post-streptococcal acute glomerulonephritis is found in children aged 2-10 years, with hypertension as the most common clinical manifestation. In addition, microscopic hematuria is the most commonly detected laboratory disorder. This study provides a useful picture for medical personnel in the diagnosis and treatment of acute glomerulonephritis, as well as educating parents about the importance of handling respiratory tract infections that can trigger this disease.

Recommendations

Based on the findings of this study, the following recommendations are made:

Medical personnel should be aware of the clinical manifestations of post-streptococcal acute glomerulonephritis, particularly hypertension and microscopic hematuria.
Parents should be educated about the importance of handling respiratory tract infections that can trigger post-streptococcal acute glomerulonephritis.
Further research is needed to understand the underlying mechanisms of post-streptococcal acute glomerulonephritis and to develop effective treatments for the disease.

Limitations

This study has several limitations, including:

The study was conducted in a single hospital and may not be representative of the general population.
The study relied on retrospective data and may be subject to biases.
The study did not control for potential confounding variables.

Future Directions

Future studies should aim to:

Investigate the underlying mechanisms of post-streptococcal acute glomerulonephritis.
Develop effective treatments for the disease.
Conduct larger, more representative studies to confirm the findings of this study.

References

[List of references cited in the study]

Appendix

[Appendix materials, including additional tables and figures]
Q&A: Post-Streptococcal Acute Glomerulonephritis in Children

Introduction

Post-streptococcal acute glomerulonephritis (GNAPS) is a common kidney disease that affects children worldwide. It is characterized by inflammation of the glomerulus, a vital part of the kidney responsible for filtering waste from the blood. In this Q&A article, we will address some of the most frequently asked questions about post-streptococcal acute glomerulonephritis in children.

Q: What is post-streptococcal acute glomerulonephritis (GNAPS)?

A: GNAPS is a kidney disease that occurs after a streptococcal infection, such as strep throat or skin infections. It is characterized by inflammation of the glomerulus, a vital part of the kidney responsible for filtering waste from the blood.

Q: What are the symptoms of GNAPS?

A: The symptoms of GNAPS can vary, but common symptoms include:

High blood pressure (hypertension)
Blood in the urine (hematuria)
Swelling in the legs and feet (edema)
Decreased urine output (oliguria)
Fatigue
Loss of appetite

Q: What are the risk factors for GNAPS?

A: The risk factors for GNAPS include:

Age: Children under the age of 10 are more likely to develop GNAPS.
Sex: Boys are more likely to develop GNAPS than girls.
Family history: Children with a family history of GNAPS are more likely to develop the disease.
Previous streptococcal infections: Children who have had previous streptococcal infections are more likely to develop GNAPS.

Q: How is GNAPS diagnosed?

A: GNAPS is diagnosed through a combination of physical examination, medical history, and laboratory tests. Laboratory tests may include:

Urine tests to check for blood and protein in the urine
Blood tests to check for kidney function and inflammation
Imaging tests, such as ultrasound or CT scans, to check for kidney damage

Q: What is the treatment for GNAPS?

A: The treatment for GNAPS typically involves:

Rest and hydration
Medications to control blood pressure and reduce inflammation
Medications to prevent further kidney damage
Follow-up appointments with a healthcare provider to monitor kidney function and adjust treatment as needed

Q: Can GNAPS be prevented?

A: While there is no surefire way to prevent GNAPS, there are steps that can be taken to reduce the risk of developing the disease. These include:

Getting regular check-ups with a healthcare provider
Practicing good hygiene, such as washing hands frequently
Getting vaccinated against streptococcal infections
Avoiding close contact with people who have streptococcal infections

Q: What is the prognosis for children with GNAPS?

A: The prognosis for children with GNAPS is generally good, with most children making a full recovery. However, some children may experience long-term kidney damage or other complications.

Q: Can GNAPS recur?

A: Yes, GNAPS can recur. Children who have had GNAPS are more likely to develop the disease again in the future.

Q: What is the role of parents in managing GNAPS?

A: Parents play a crucial role in managing GNAPS. They should:

Monitor their child's symptoms and report any changes to their healthcare provider
Ensure their child takes medications as prescribed
Encourage their child to rest and stay hydrated
Follow up with their healthcare provider regularly to monitor kidney function and adjust treatment as needed

Conclusion

Post-streptococcal acute glomerulonephritis (GNAPS) is a common kidney disease that affects children worldwide. By understanding the symptoms, risk factors, diagnosis, treatment, and prognosis of GNAPS, parents and healthcare providers can work together to manage the disease and promote a full recovery.