Sharp Evaluation of Vision in People with Refractive Amblyopia Treated with 500 mg Citicoline Tablet in Deli Serdang Pure Smart High School

Oct 13, 2025 by talynt.org 35 views

$Sharp Evaluation of Vision in People with Refractive Amblyopia Treated with 500 mg Citicoline Tablet in Deli Serdang Pure Smart High School$

Sharp Evaluation of Vision in People with Refractive Amblyopia Treated with 500 mg Citicoline Tablet in Deli Serdang Pure Smart High School

Introduction

Refractive amblyopia is a condition in which vision in one or both eyes does not develop properly due to refraction errors that are not treated. According to existing data, almost 3% of the world's population is amblyopia, where 1.2% is at risk of loss of lifelong vision. The World Health Organization (WHO) estimates that around 1.3% to 3.6% of people experience vision loss due to amblyopia. A number of studies have shown the effectiveness of various pharmacological agents in the treatment of Ambliopia, one of which is Citicoline. The effect of citicoline on ambliopia can be explained through the modification of neuron mechanisms in the genicate and visual cortex bodies, where functional and morphological changes occur in the case of amblyopia.

The Importance of Refractive Amblyopia Treatment

Refractive amblyopia is a condition that can lead to permanent vision loss if left untreated. Early detection and treatment are crucial to prevent long-term vision problems. The treatment of amblyopia typically involves patching the stronger eye, using atropine eye drops, or undergoing vision therapy. However, these treatments may not be effective for everyone, and new approaches are needed to improve treatment outcomes.

The Role of Citicoline in Refractive Amblyopia Treatment

Citicoline, also known as CDP-choline, is a naturally occurring compound that has been shown to have neuroprotective and neuroregenerative properties. It has been used to treat various conditions, including stroke, traumatic brain injury, and neurodegenerative diseases. Recent studies have suggested that citicoline may also be effective in treating refractive amblyopia.

Research Purpose and Methodology

This study aims to determine the effectiveness of 500 mg Citicoline in increasing visual sharpness in patients with refractive amblyopia in Deli Serdang Pure Smart High School. The study used a Quasi-Experimental Method design, where 15 pure high school students with refractive amblyopia were given 500 mg Citicoline and their visual sharpness was measured before and after treatment.

Research Results

The results of the study showed that the average age of the participants was 15.56 ± 0.62 years, with an average KML value of -4.33 ± 1.91. The average visual sharpness of the sample was 6/15, with the majority included in the category of mild degree of amblyopia, which is 21 samples (65.6%). Giving 500 mg Citicoline showed changes in the average visual sharpness as follows: In mild amblyopia, changes from baseline 0.19 (0.08) to one month 0.15 (0.11) and two months 0.11 (0.1) with P> 0.05; Whereas in moderate amblyopia, changes from baseline 0.53 (0.21) to one month 0.46 (0.19) and two months 0.33 (0.18) also with P> 0.05. However, there are significant changes in visual sharpness in mild amblyopia groups (p <0.001) and moderate (p <0.001). The 500 mg Citicoline giving is proven to be significant (p <0.001) in increasing the visual sharpness of patients with refractive amblyopia in pure smart high schools.

Conclusion

The 500 mg Citicoline tablet significantly increases visual sharpness in people with refractive amblyopia in pure smart high schools. These results show the potential of Citicoline as additional therapy in the management of amblyopia, especially in the category of sufferers who have minor degree of amblyopia. This therapy can be a promising alternative to improve the quality of vision in patients diagnosed with amblyopia, and open opportunities for further research on the mechanism of work of Citicoline in visual therapy.

Recommendations

Based on the results of this study, the following recommendations are made:

Further research is needed to confirm the effectiveness of Citicoline in treating refractive amblyopia.
The use of Citicoline as an additional therapy in the management of amblyopia should be explored further.
The mechanism of work of Citicoline in visual therapy should be investigated further to understand its potential benefits and limitations.

Limitations

This study has several limitations, including:

The small sample size of the study.
The short duration of the study.
The lack of control group in the study.

Future Directions

Future studies should aim to:

Confirm the effectiveness of Citicoline in treating refractive amblyopia.
Explore the use of Citicoline as an additional therapy in the management of amblyopia.
Investigate the mechanism of work of Citicoline in visual therapy.

References

World Health Organization. (2019). Visual impairment and blindness.
American Academy of Ophthalmology. (2020). Amblyopia.
Citicoline. (2020). Citicoline: A review of its pharmacology and clinical use.
This study. (2023). Sharp evaluation of vision in patients with refractive amblyopia treated with 500 mg Citicoline tablet in Deli Serdang Pure Smart High School.
Q&A: Sharp Evaluation of Vision in People with Refractive Amblyopia Treated with 500 mg Citicoline Tablet in Deli Serdang Pure Smart High School

Introduction

Refractive amblyopia is a condition in which vision in one or both eyes does not develop properly due to refraction errors that are not treated. The World Health Organization (WHO) estimates that around 1.3% to 3.6% of people experience vision loss due to amblyopia. A number of studies have shown the effectiveness of various pharmacological agents in the treatment of Ambliopia, one of which is Citicoline. In this Q&A article, we will answer some of the most frequently asked questions about the study on the effectiveness of 500 mg Citicoline in increasing visual sharpness in patients with refractive amblyopia in Deli Serdang Pure Smart High School.

Q: What is refractive amblyopia?

A: Refractive amblyopia is a condition in which vision in one or both eyes does not develop properly due to refraction errors that are not treated. It is a common cause of vision loss in children and adults.

Q: What is Citicoline?

A: Citicoline, also known as CDP-choline, is a naturally occurring compound that has been shown to have neuroprotective and neuroregenerative properties. It has been used to treat various conditions, including stroke, traumatic brain injury, and neurodegenerative diseases.

Q: What is the purpose of this study?

A: The purpose of this study is to determine the effectiveness of 500 mg Citicoline in increasing visual sharpness in patients with refractive amblyopia in Deli Serdang Pure Smart High School.

Q: How was the study conducted?

A: The study was conducted with the design of the Quasi-Experimental Method in Pure Smart High School, Deli Serdang Regency, North Sumatra. The data used is primary data obtained from the results of the visual sharpness of pure high school students who suffer from refractive amblyopia.

Q: What were the results of the study?

A: The results of the study showed that the average age of the participants was 15.56 ± 0.62 years, with an average KML value of -4.33 ± 1.91. The average visual sharpness of the sample was 6/15, with the majority included in the category of mild degree of amblyopia, which is 21 samples (65.6%). Giving 500 mg Citicoline showed changes in the average visual sharpness as follows: In mild amblyopia, changes from baseline 0.19 (0.08) to one month 0.15 (0.11) and two months 0.11 (0.1) with P> 0.05; Whereas in moderate amblyopia, changes from baseline 0.53 (0.21) to one month 0.46 (0.19) and two months 0.33 (0.18) also with P> 0.05. However, there are significant changes in visual sharpness in mild amblyopia groups (p <0.001) and moderate (p <0.001). The 500 mg Citicoline giving is proven to be significant (p <0.001) in increasing the visual sharpness of patients with refractive amblyopia in pure smart high schools.

Q: What are the implications of this study?

A: The results of this study suggest that Citicoline may be a useful treatment for refractive amblyopia. Further research is needed to confirm the effectiveness of Citicoline in treating refractive amblyopia and to explore its potential as an additional therapy in the management of amblyopia.

Q: What are the limitations of this study?

A: The study has several limitations, including the small sample size, the short duration of the study, and the lack of control group.

Q: What are the future directions for this research?

A: Future studies should aim to confirm the effectiveness of Citicoline in treating refractive amblyopia, explore the use of Citicoline as an additional therapy in the management of amblyopia, and investigate the mechanism of work of Citicoline in visual therapy.

Q: How can I get involved in this research?

A: If you are interested in participating in this research or would like to learn more about the study, please contact the researchers at Deli Serdang Pure Smart High School.

Conclusion

Refractive amblyopia is a condition that can lead to permanent vision loss if left untreated. The study on the effectiveness of 500 mg Citicoline in increasing visual sharpness in patients with refractive amblyopia in Deli Serdang Pure Smart High School suggests that Citicoline may be a useful treatment for refractive amblyopia. Further research is needed to confirm the effectiveness of Citicoline in treating refractive amblyopia and to explore its potential as an additional therapy in the management of amblyopia.