The Suitability of the Results between the Skewer Test and the Atopic Mittle Patch Test in the House of the House in Patients with Atopic Dermatitis

Oct 13, 2025 by talynt.org 12 views

The Suitability of the Results between the Skewer Test and the Atopic Mittle Patch Test in the House of the House in Patients with Atopic Dermatitis

Introduction

Atopic dermatitis (DA) is a chronic inflammatory skin disease that is often associated with an atopic history. In recent years, an increase in exposure to pollutants and allergens in the room is thought to be the cause of increasing DA frequency. One of the most frequently associated allergens as a trigger for the house is the dust mites of the house, which can be identified through two types of tests: Skin Prick Test and Atopy Patch Test (Atophy Patch Test). This study aims to determine the compatibility between the results of the skin puncture test and atopic patch test in patients with atopic dermatitis.

Research Purposes

The primary objective of this study is to investigate the suitability of the results between the skewer test and the atopic mittle patch test in the house of the house in patients with atopic dermatitis. This study aims to provide a comprehensive understanding of the compatibility between the two test methods and their limitations in detecting allergens that play a role in atopic dermatitis.

Research Methods

This study is a descriptive analytic study with a cross-sectional design conducted between June 2008 and May 2009. The research subject consists of patients who are more than 14 years old and meet the inclusion criteria. The total sample studied was 28 people. The first step is to do a skin stab test, which was carried out on the inside of the forearm using a solution of allergen dermatophagoides pteronyssinus 3%, dermatophagoides Farinae 100 IR/ml, and histamine solution 1 mg/ml as positive control, and phosphate buffer solution as a negative control. The results are read after 15 minutes. The positive level is determined according to the AAS and Belin method.

Furthermore, an atopic patch test was carried out using a 30% dermatophagoides allergen extract mixed with petrolatum, applied to the van der bend chamber on the back. The results are read after 48 and 72 hours, with a positive level determined based on the criteria for European Task Task Force on atopic dermatitis (ETFAD). The data obtained is then analyzed further.

Research Result

Of the 28 DA patients who are more than 14 years old and meet the inclusion criteria, most patients (28.6%) are in the group of 31-38 years, with an average age of 32.3 years. The results of the skin puncture test showed that 22 people (78.6%) were positive against D. Pteronyssinus and D. Farinae, with various positive levels. In the atopic patch test, positive results after 48 hours were obtained in 13 patients (46.4%), while after 72 hours, there were 17 patients with positive results (60.7%).

The data sensitivity data of the Atopy patch test is 59%, 33% specificity, positive predictive value 76%, 18% negative predictive value, positive possibility ratio of 0.89, a negative possibility ratio of 1.23, and Kappa -0.058 value.

Conclusion

Based on the results of the study, there is no compatibility between the results of the skin puncture test and atopic patch test in patients with atopic dermatitis. These findings indicate that the two test methods have different characteristics and do not replace each other in detecting allergens that play a role in atopic dermatitis.

Through this study, it is important for health practitioners to understand the limitations of each method and consider the combination of the use of the two tests to obtain more comprehensive information about allergen sensitivity in atopic dermatitis patients. Further research is needed to explore the factors that can affect the results of these two types of tests, as well as to develop a more effective management strategy for patients.

Implications of the Study

The findings of this study have significant implications for the diagnosis and management of atopic dermatitis. The results suggest that the skin prick test and atopic patch test are not interchangeable and should be used in conjunction with each other to obtain a more comprehensive understanding of allergen sensitivity in patients with atopic dermatitis.

Limitations of the Study

This study has several limitations that should be acknowledged. The sample size was relatively small, and the study was conducted in a single setting. Further research is needed to replicate the findings of this study and to explore the generalizability of the results to other populations.

Future Research Directions

Future research should focus on exploring the factors that affect the results of the skin prick test and atopic patch test, as well as developing a more effective management strategy for patients with atopic dermatitis. Additionally, further research is needed to investigate the use of other diagnostic tests, such as the patch test, in the diagnosis of atopic dermatitis.

Recommendations for Health Practitioners

Health practitioners should be aware of the limitations of each test method and consider the combination of the use of the two tests to obtain more comprehensive information about allergen sensitivity in atopic dermatitis patients. Additionally, health practitioners should be aware of the factors that can affect the results of these two types of tests and take these factors into account when interpreting the results.

Conclusion

In conclusion, this study found that there is no compatibility between the results of the skin puncture test and atopic patch test in patients with atopic dermatitis. The findings of this study have significant implications for the diagnosis and management of atopic dermatitis, and highlight the need for further research to explore the factors that affect the results of these two types of tests.
Frequently Asked Questions (FAQs) about the Suitability of the Results between the Skewer Test and the Atopic Mittle Patch Test in the House of the House in Patients with Atopic Dermatitis

Q: What is atopic dermatitis (DA)?

A: Atopic dermatitis (DA) is a chronic inflammatory skin disease that is often associated with an atopic history. It is characterized by dry, itchy, and scaly skin, and can be triggered by various factors, including allergens, stress, and environmental factors.

Q: What are the two types of tests used to identify allergens that play a role in atopic dermatitis?

A: The two types of tests used to identify allergens that play a role in atopic dermatitis are the skin prick test and the atopic patch test. The skin prick test involves pricking the skin with a small amount of allergen, while the atopic patch test involves applying a small amount of allergen to the skin and observing the reaction over a period of time.

Q: What are the limitations of the skin prick test?

A: The skin prick test has several limitations, including its inability to detect delayed-type hypersensitivity reactions, which can occur several days after exposure to an allergen. Additionally, the skin prick test may not be suitable for patients with sensitive skin or those who have had previous skin reactions to allergens.

Q: What are the limitations of the atopic patch test?

A: The atopic patch test has several limitations, including its inability to detect immediate-type hypersensitivity reactions, which can occur within minutes of exposure to an allergen. Additionally, the atopic patch test may not be suitable for patients with sensitive skin or those who have had previous skin reactions to allergens.

Q: What are the implications of the study for the diagnosis and management of atopic dermatitis?

A: The study suggests that the skin prick test and atopic patch test are not interchangeable and should be used in conjunction with each other to obtain a more comprehensive understanding of allergen sensitivity in patients with atopic dermatitis. This is because the two tests have different characteristics and may detect different types of allergic reactions.

Q: What are the implications of the study for health practitioners?

A: The study suggests that health practitioners should be aware of the limitations of each test method and consider the combination of the use of the two tests to obtain more comprehensive information about allergen sensitivity in atopic dermatitis patients. Additionally, health practitioners should be aware of the factors that can affect the results of these two types of tests and take these factors into account when interpreting the results.

Q: What are the future research directions for atopic dermatitis?

A: Future research should focus on exploring the factors that affect the results of the skin prick test and atopic patch test, as well as developing a more effective management strategy for patients with atopic dermatitis. Additionally, further research is needed to investigate the use of other diagnostic tests, such as the patch test, in the diagnosis of atopic dermatitis.

Q: What are the recommendations for health practitioners?

A: Health practitioners should be aware of the limitations of each test method and consider the combination of the use of the two tests to obtain more comprehensive information about allergen sensitivity in atopic dermatitis patients. Additionally, health practitioners should be aware of the factors that can affect the results of these two types of tests and take these factors into account when interpreting the results.

Q: What are the potential applications of the study?

A: The study has potential applications in the diagnosis and management of atopic dermatitis, as well as in the development of new diagnostic tests and treatments for the condition. Additionally, the study may have implications for the development of new treatments for other allergic conditions.

Q: What are the potential limitations of the study?

A: The study has several limitations, including its small sample size and the fact that it was conducted in a single setting. Additionally, the study may not be generalizable to other populations, and further research is needed to replicate the findings and explore the generalizability of the results.

Q: What are the potential future directions for the study?

A: The study has potential future directions, including the exploration of the factors that affect the results of the skin prick test and atopic patch test, as well as the development of a more effective management strategy for patients with atopic dermatitis. Additionally, further research is needed to investigate the use of other diagnostic tests, such as the patch test, in the diagnosis of atopic dermatitis.